Eternal Darkness: Sanity's Requiem

Eternal Darkness: Sanity's Requiem is a psychological horror video game released for the Nintendo GameCube, developed by Canadian developer Silicon Knights and originally planned for the Nintendo 64. It was the first video game published directly by Nintendo, rather than a third-party developer, to be rated M for mature by the Entertainment Software Rating Board.

Hang Post Initial Quote
Since, Dolphin will hang in Dualcore and SyncGPU modes when the Edgar Allen Poe quote displays. Refer. Use Deterministic GPU or Single Core to avoid the issue.

Green Transitions
Before and after a chapter, the screen momentarily turns green. This is harmless, but not intended, so turn on the real XFB if you can handle it.

Transparency issues
In Lindsey's section the character can sometimes disappear when underneath hanging vines. Fix by turning on Per-Pixel Lighting for this section.