Paper Mario: The Thousand-Year Door

Paper Mario: The Thousand-Year Door, released in Japan as Paper Mario RPG, is a console role-playing game developed by Intelligent Systems and published by Nintendo for the Nintendo GameCube. The Thousand-Year Door is the fourth game in the Mario RPG series and the second in the Paper Mario series.

Professor Frankly's Gate
The gate outside Professor Frankly's house turns into a cyan block, and then disappears when he is opening it to show you the Thousand-Year Door.

Dance with the Invisible Princess
When TEC asks you to dance with the hologram of the Princess (end of Chapter 2), the hologram appears only if the EFB Copy is set to Texture.

Punies
The Punies may display incorrectly on all backends. EFB to Texture displays garbage, while EFB to Ram shows the Punies but distorts them. Fortunately this doesn't affect all punies at all times, but it is common. See.

Sound Issues
DSP HLE may have audio crackling after extended play. Use DSP LLE to avoid this.

Cache Display Lists
Enabling Cache Display Lists causes bounding box glitches.