Dr. Mario Online RX

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Dr. Mario Online RX
Developer(s) Arika
Publisher(s) Nintendo
Platform(s) WiiWare
Release date(s) JP March 25, 2008
NA May 26, 2008
EU May 20, 2008
AUS May 20, 2008
Genre(s) Puzzle
Mode(s) Single-player, Co-op (4), Online (4)
Input methods Wii Remote, Wii Remote + Nunchuk, Classic Controller, GameCube Controller
Compatibility 5Stars5.pngEdit rating: Dr. Mario Online RX
See also...

Dolphin Forum thread
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Dr. Mario Online Rx, released as Dr. MARIO & 細菌撲滅 (Dokutā Mario & Saikin Bokumetsu, lit. "Dr. Mario & Bacteria Extermination") in Japan and as Dr. Mario & Germ Buster in Europe and Australia, is a puzzle video game starring Dr. Mario. As with other Dr. Mario games, players must manipulate pills to destroy colored viruses in the game area. This game also features a version of the Nintendo DS title Brain Age 2's "Virus Buster/Germ Buster" mini-game, which uses the pointer function of the Wii Remote to move pills, and now allows up to four players to participate cooperatively.

The title supports the Nintendo Wi-Fi Connection service, allowing players to compete with one another over the Internet. Players can also use Mii characters or Dr. Mario during gameplay.


There are no reported problems with this title.


This title does not need non-default settings to run properly.

Version Compatibility

The graph below charts the compatibility with Dr. Mario Online RX since Dolphin's 2.0 release, listing revisions only where a compatibility change occurred.

5.0-21717 (current)
2.0 (r5384)
Compatibility can be assumed to align with the indicated revisions. However, compatibility may extend to prior revisions or compatibility gaps may exist within ranges indicated as compatible due to limited testing. Please update as appropriate.


This title has been tested on the environments listed below:

Test Entries
Revision OS CPU GPU Result Tester
r4770 Windows XP Intel Core 2 Duo E7400 @ 2.8 GHz NVIDIA GeForce 9600 GT Dr. Mario Online Rx (WiiWare) on Dolphin SVN R 3950 - Nintendo Wii Emulator dTerenciano
2.0 Windows XP AMD Athlon II x2 215 @ 3.56 GHz NVIDIA GeForce GT 440 Work's at 100% of speed. No glitches, but is this OK what 3D Wii-Mii - has no eyes? only glases on empty face. †.fl.l).
4.0-1349 Windows 8 AMD FX 6300 @ 4.3 GHz AMD Radeon HD 6450 Playable. 60FPS. Faefdsedf

Gameplay Videos